We propose a method for non-parametric conditional distribution estimation based on partitioning covariate-sorted observations into contiguous bins and using the within-bin empirical CDF as the predictive distribution. Bin boundaries are chosen to minimise the total leave-one-out Continuous Ranked Probability Score (LOO-CRPS), which admits a closed-form cost function with $O(n^2 \log n)$ precomputation and $O(n^2)$ storage; the globally optimal $K$-partition is recovered by a dynamic programme in $O(n^2 K)$ time. Minimisation of within-sample LOO-CRPS turns out to be inappropriate for selecting $K$ as it results in in-sample optimism. We instead select $K$ by $K$-fold cross-validation of test CRPS, which yields a U-shaped criterion with a well-defined minimum. Having selected $K^*$ and fitted the full-data partition, we form two complementary predictive objects: the Venn prediction band and a conformal prediction set based on CRPS as the nonconformity score, which carries a finite-sample marginal coverage guarantee at any prescribed level $\varepsilon$. The conformal prediction is transductive and data-efficient, as all observations are used for both partitioning and p-value calculation, with no need to reserve a hold-out set. On real benchmarks against split-conformal competitors (Gaussian split conformal, CQR, CQR-QRF, and conformalized isotonic distributional regression), the method produces substantially narrower prediction intervals while maintaining near-nominal coverage.

In the near future, Structural Health Monitoring (SHM) technologies will be capable of overcoming the drawbacks in the current maintenance and life-cycle management paradigms, namely: cost, increased downtime, less-than-optimal safety management paradigm and the limited applicability of fully-autonomous operations. In the context of SHM, one of the most challenging tasks is damage quantification. Current methods face accuracy and/or robustness issues when it comes to varying operating and environmental conditions. In addition, the damage/no-damage paradigm of current frameworks does not offer much information to maintainers on the ground for proper decision-making. In this study, a novel structural damage quantification framework is proposed based on widely-used Damage Indices (DIs) and Gaussian Process Regression Models (GPRMs). The novelty lies in calculating the probability of an incoming test DI point originating from a specific state, which allows for probability-educated decision-making. This framework is applied to three test cases: a Carbon Fiber-Reinforced Plastic (CFRP) coupon with attached weights as simulated damage, an aluminum coupon with a notch, and an aluminum coupon with attached weights as simulated damage under varying loading states. The state prediction method presented herein is applied to single-state quantification in the first two test cases, as well as the third one assuming the loading state is known. Finally, the proposed method is applied to the third test case assuming neither the damage size nor the load is known in order to predict both simultaneously from incoming DI test points. In applying this framework, two forms of GPRMs (standard and variational heteroscedastic) are used in order to critically assess their performances with respect to the three test cases.

Pneumonia is a leading cause of illness and death in children, underscoring the need for early and accurate detection. In this study, we propose a novel lightweight ensemble model for detecting pneumonia in children using chest X-ray images. This ensemble model integrates two pre-trained convolutional neural networks (CNNs), MobileNetV2 and NASNetMobile, selected for their balance of computational efficiency and accuracy. These models were fine-tuned on a pediatric chest X-ray dataset and combined to enhance classification performance. Our proposed ensemble model achieved a classification accuracy of 98.63%, significantly outperforming individual models such as MobileNetV2 (97.10%) and NASNetMobile(96.25%) in terms of accuracy, precision, recall, and F1 score. Moreover, the ensemble model outperformed state-of-the-art architectures, including ResNet50, InceptionV3, and DenseNet201, while maintaining computational efficiency. The proposed lightweight ensemble model presents a highly effective and resource-efficient solution for pneumonia detection, making it particularly suitable for deployment in resource-constrained settings.

Lightweight deep learning approaches for malaria detection have gained attention for their potential to enhance diagnostics in resource constrained environments. For our study, we selected SqueezeNet1.1 as it is one of the most popular lightweight architectures. SqueezeNet1.1 is a later version of SqueezeNet1.0 and is 2.4 times more computationally efficient than the original model. We proposed and implemented three ultra-lightweight architecture variants to SqueezeNet1.1 architecture, namely Variant 1 (one fire module), Variant 2 (two fire modules), and Variant 3 (four fire modules), which are even more compact than SqueezeNetV1.1 (eight fire modules). These models were implemented to evaluate the best performing variant that achieves superior computational efficiency without sacrificing accuracy in malaria blood cell classification. The models were trained and evaluated using the NIH Malaria dataset. We assessed each model's performance based on metrics including accuracy, recall, precision, F1-score, and Area Under the Curve (AUC). The results show that the SqueezeNet1.1 model achieves the highest performance across all metrics, with a classification accuracy of 97.12%. Variant 3 (four fire modules) offers a competitive alternative, delivering almost identical results (accuracy 96.55%) with a 6x reduction in computational overhead compared to SqueezeNet1.1. Variant 2 and Variant 1 perform slightly lower than Variant 3, with Variant 2 (two fire modules) reducing computational overhead by 28x, and Variant 1 (one fire module) achieving a 54x reduction in trainable parameters compared to SqueezeNet1.1. These findings demonstrate that our SqueezeNet1.1 architecture variants provide a flexible approach to malaria detection, enabling the selection of a variant that balances resource constraints and performance.

Early detection of COVID-19 is crucial for effective treatment and controlling its spread. This study proposes a novel hybrid deep learning model for detecting COVID-19 from CT scan images, designed to assist overburdened medical professionals. Our proposed model leverages the strengths of VGG16, DenseNet121, and MobileNetV2 to extract features, followed by Principal Component Analysis (PCA) for dimensionality reduction, after which the features are stacked and classified using a Support Vector Classifier (SVC). We conducted comparative analysis between the proposed hybrid model and individual pre-trained CNN models, using a dataset of 2,108 training images and 373 test images comprising both COVID-positive and non-COVID images. Our proposed hybrid model achieved an accuracy of 98.93%, outperforming the individual models in terms of precision, recall, F1 scores, and ROC curve performance.

Understanding the neurobiology of opioid use disorder (OUD) using resting-state functional magnetic resonance imaging (rs-fMRI) may help inform treatment strategies to improve patient outcomes. Recent literature suggests temporal characteristics of rs-fMRI blood oxygenation level-dependent (BOLD) signals may offer complementary information to functional connectivity analysis. However, existing studies of OUD analyze BOLD signals using measures computed across all time points. This study, for the first time in the literature, employs data-driven machine learning (ML) modeling of rs-fMRI BOLD features representing multiple time points to identify region(s) of interest that differentiate OUD subjects from healthy controls (HC). Following the triple network model, we obtain rs-fMRI BOLD features from the default mode network (DMN), salience network (SN), and executive control network (ECN) for 31 OUD and 45 HC subjects. Then, we use the Boruta ML algorithm to identify statistically significant BOLD features that differentiate OUD from HC, identifying the DMN as the most salient functional network for OUD. Furthermore, we conduct brain activity mapping, showing heightened neural activity within the DMN for OUD. We perform 5-fold cross-validation classification (OUD vs. HC) experiments to study the discriminative power of functional network features with and without fusing demographic features. The DMN shows the most discriminative power, achieving mean AUC and F1 scores of 80.91% and 73.97%, respectively, when fusing BOLD and demographic features. Follow-up Boruta analysis using BOLD features extracted from the medial prefrontal cortex, posterior cingulate cortex, and left and right temporoparietal junctions reveals significant features for all four functional hubs within the DMN.

A community needs assessment is a tool used by non-profits and government agencies to quantify the strengths and issues of a community, allowing them to allocate their resources better. Such approaches are transitioning towards leveraging social media conversations to analyze the needs of communities and the assets already present within them. However, manual analysis of exponentially increasing social media conversations is challenging. There is a gap in the present literature in computationally analyzing how community members discuss the strengths and needs of the community. To address this gap, we introduce the task of identifying, extracting, and categorizing community needs and assets from conversational data using sophisticated natural language processing methods. To facilitate this task, we introduce the first dataset about community needs and assets consisting of 3,511 conversations from Reddit, annotated using crowdsourced workers. Using this dataset, we evaluate an utterance-level classification model compared to sentiment classification and a popular large language model (in a zero-shot setting), where we find that our model outperforms both baselines at an F1 score of 94% compared to 49% and 61% respectively. Furthermore, we observe through our study that conversations about needs have negative sentiments and emotions, while conversations about assets focus on location and entities. The dataset is available at https://github.com/towhidabsar/CommunityNeeds.

Recent continual learning approaches have primarily focused on mitigating catastrophic forgetting. Nevertheless, two critical areas have remained relatively unexplored: 1) evaluating the robustness of proposed methods and 2) ensuring the security of learned tasks. This paper investigates the susceptibility of continually learned tasks, including current and previously acquired tasks, to adversarial attacks. Specifically, we have observed that any class belonging to any task can be easily targeted and misclassified as the desired target class of any other task. Such susceptibility or vulnerability of learned tasks to adversarial attacks raises profound concerns regarding data integrity and privacy. To assess the robustness of continual learning approaches, we consider continual learning approaches in all three scenarios, i.e., task-incremental learning, domain-incremental learning, and class-incremental learning. In this regard, we explore the robustness of three regularization-based methods, three replay-based approaches, and one hybrid technique that combines replay and exemplar approaches. We empirically demonstrated that in any setting of continual learning, any class, whether belonging to the current or previously learned tasks, is susceptible to misclassification. Our observations identify potential limitations of continual learning approaches against adversarial attacks and highlight that current continual learning algorithms could not be suitable for deployment in real-world settings.

Our test sets were too small and too haphazard to support statistically valid conclusions, but they were suggestive of a number of conclusions. We summarize these here, and discuss them at greater length in section 7. Over the kinds of problems tested, GPT-4 with either plug-in is significantly stronger than GPT-4 by itself, or, almost certainly, than any AI that existed a year ago. However it is still far from reliable; it often outputs a wrong answer or fails to output any answer. In terms of overall score, we would judge that these systems performs on the level of a middling undergraduate student. However, their capacities and weaknesses do not align with a human student; the systems solve some problems that even capable students would find challenging, whereas they fail on some problems that even middling high school students would find easy.

Data-driven automated laboratories, also called self-driving laboratories, can significantly accelerate molecular synthesis and materials discovery. A key technical challenge of fully autonomous and artificial intelligenceassisted laboratory design is to effectively collect and utilize data from multiple complex processes in order to inform future experimentation. One long-standing template for utilizing experimental and simulation data is the multiresponse surface methodology (RSM) [13], whereby initial data sets are gathered through design of experiments and then statistical models are built for each quantity of interest, analyzed, and hypothesis tested iteratively. In modern scientific and engineering settings, several common paradigms could be considered as specific implementations of this discovery framework, the most common of which are active learning and modelbased optimization techniques such as Bayesian optimization. To account for multiple competing criteria, we utilize an active learning framework based in multiobjective optimization, which utilizes surrogates (such as Gaussian processes), optimization solvers, and multicriteria data acquisition in a closed feedback loop.